Check for new publications from X-MTB Consortium at NCBI

2005

Smialowski P, Schmidt T, Cox J, Kirschner A, Frishman D. Will my protein crystallize? A sequence-based predictor. Proteins. 2005 Nov 28; [Epub ahead of print]
 

Manger M, Scheck M, Prinz H, von Kries JP, Langer T, Saxena K, Schwalbe H, Furstner A, Rademann J, Waldmann H. Discovery of Mycobacterium tuberculosis protein tyrosine phosphatase A (MptpA) inhibitors based on natural products and a fragment-based approach. Chembiochem. 2005 Oct;6(10):1749-53.
 

Kefala G, Perry LJ, Weiss MS. Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of LysA (Rv1293) fromMycobacterium tuberculosis. Acta Crystallographica F 2005 July; 61(8)  782-784 
 

Kefala G, Janowski R, Panjikar S, Mueller-Dieckmann C, Weiss MS.  Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of DapB (Rv2773c) fromMycobacterium tuberculosis.Acta Crystallographica F 2005 July; 61(7)  718-721 
 

Morth JP, Gosmann S, Nowak E, Tucker PA. A novel two-component system found in Mycobacterium tuberculosis. FEBS Lett. 2005 Aug 1;579(19):4145-8.
 

Singh RK, Kefala G, Janowski R, Muelle-Dieckmann C, von Kries JP, Weiss MS. The High-Resolution Structure of LeuB (Rv2995c) from Mycobacterium tuberculosis. J Mol Biol. 2005 Feb 11;346(1):1-11. Epub 2004 Dec 23.
 

2004

Kaufmann, S.H.E.: Novel vaccination strategies against tuberculosis. Novel vaccination Strategies (Kaufmann, S.H.E., ed.), Wiley-VCH, 463-477 (2004)
 

Kaufmann, S.H.E. and H.-W. Mittruecker: Vaccination against tuberculosis: Current status and future promise.  Am J Respir Crit Care Med. 25: 345-352 (2004)
 

Kaufmann, S.H.E.: New Issues in Tuberculosis. Ann. Rheum. Dis. 63: ii50-ii56 (2004)
 

Kaufmann, S.H.E. and J.L. Flynn: CD8 T Cells in Tuberculosis.  Tuberculosis and the Tubercle Bacillus (S. Cole, K. Davies Eisenach, D. N. McMurray, W.R. Jacobs eds.), ASM Press, Washington, 465-474 (2004) 
 

Kaufmann, S.H.E.: Impfstoff-Entwicklung gegen Tuberkulose: Ein altes, noch immer aktuelles Thema. Jahrbuch 2003 der Deutschen Akademie der Naturforscher Leopoldina, Leopoldina Reihe 3, 49: 537-553 (2004) 
 

Morth JP, Morth JP, Feng V, Perry LJ, Svergun DI, Tucker PA. The crystal and solution structure of a putative transcriptional antiterminator from Mycobacterium tuberculosis. Structure (Camb). 2004 Sep;12(9):1595-605. 1;579(19):4145-8.
 

Morth JP, Feng V, Perry LJ, Svergun DI, Tucker PA. (2004). The Crystal and Solution Structure of a Putative Transcriptional Antiterminator from Mycobacterium tuberculosis. Structure (Camb). 12(9):1595-605.
 

Roese, L., S.H.E. Kaufmann and Sabine Daugelat: Involvement of Mycobacterium smegmatis undecaprenyl phosphokinase in biofilm and smegma formation. Microbes Infect. 6: 965-971 (2004)
 

Ulrichs, T. and S.H.E. Kaufmann: Cell-mediated immune response. In: Tuberculosis (N.R. Rom, S.M. Garay and B.R. Bloom, eds.), 2nd edition, Lippincott Williams & Wilkins, Philadelphia: 251-262 (2004)
 

Ulrichs, T., G.A. Kosmiadi, V. Trusov, S. Joerg, L. Pradl, M. Titukhina, V. Mishenko, N. Gushina and S.H.E. Kaufmann: Human tuberculous granulomas induce peripheral lymphoid follicle-like structures to orchestrate local host-defense in the lung. J. Pathol. 204: 217-228 (2004)
 

Kaufmann, S.H.E. (2000). Is the development of new tuberculosis vaccine possible Nature Med. 6: 955-960.
 

Collins, H.L. and S.H.E. Kaufmann (2001). The many faces of host responses to tuberculosis. Immunology 103: 1-9.
 

Collins, H.L. and S.H.E. Kaufmann (2001). Prospects for better tuberculosis vaccines. The Lancet Infect. Dis 1: 21-28.
 

Kaufmann, S.H.E. (2001). How can immunology contribute to the control of tuberculosis? Nature Rev. Immunol. 1: 20-30.
 

Ulrichs, T., and S.H.E. Kaufmann (2002). Mycobacterial persistence and immunity. Front. Biosci. 7: D458-69.
 

Jungblut, P.R., U.E. Schaible, H.-J. Mollenkopf, U. Zimny-Arndt, B. Raupach, J. Mattow, P. Halada, S. Lamer, K. Hagens, and S.H.E. Kaufmann (2001). Comparative proteome analysis of Mycobacterium tuberculosis and Mycobacterium bovis BCG strains: Towards functional genomics of microbial pathogens. Mol. Microbiol. 33: 1103-1117.
 

Mollenkopf, H.-J., P.R. Jungblut, B. Raupach, J. Mattow, S. Lamer, U. Zimny-Arndt, U.E. Schaible, and S.H.E. Kaufmann (2001). A dynamic 2D-PAGE database: The mycobacterial proteome via internet. Electrophoresis 20: 2172-2180.
 

Mattow, J., P.R. Jungblut, E.-C. Müler, and S.H.E. Kaufmann (2001). Identification of acidic, low molecular mass protein of Mycobacterium tuberculosis strain H37Rv by MALDI- and ESI-mass spectrometry. Proteomics 1: 494-507.
 

Jungblut, P., E.-C. Müler, J. Mattow, and S.H.E. Kaufmann (2001). Proteomics reveals open reading frames in Mycobacterium tuberculosis H37Rv not predicted by genomics. Infect. Immun. 69: 5905-5907.
 

Mattow, J., P.R. Jungblut, U.E. Schaible, H.-J. Mollenkopf, S. Lamer, U. Zimny-Arndt, K. Hagens, E.-C. Müler, and S.H.E. Kaufmann (1998). Identification of proteins from Mycobacterium tuberculosis missing in attenuated Mycobacterium bovis BCG strains. Electrophoresis 22: 2936-2946.
 

Hess, J., D. Miko, A. Catic, V. Lehmensiek, D.G. Russell, and S.H.E. Kaufmann (1998). Mycobacterium bovis Bacille Calmette-Guerin strains secreting listeriolysin of Listeria monocytogenes. Proc. Natl. Acad. Sci. USA 95: 5299-5304.
 

Ulrichs, T., M.E. Munk, H. Mollenkopf, S. Behr-Perst, R. Colangeli, M.L. Gennaro, and S.H.E. Kaufmann (1998). Differential T-cell responses to Mycobacterium tuberculosis ESAT6 in tuberculosis patients and healthy donors. Eur. J. Immunol. 28: 3949-3958.
 

Hess, J., L. Grode J. Hellwig, I. Gentschev, W. Goebel, C. Ladel, and S.H.E. Kaufmann (2000). Protection against murine tuberculosis by an attenuated recombinant Salmonella typhimurium vaccine strain that secretes the 30 kDa-antigen of Mycobacterium bovis BCG. FEMS Immunol. Med. Microbiol. 27: 283-289.
 

Grode, L., M. Kursar, J. Fensterle, S.H.E. Kaufmann and J. Hess (1998). Cell-mediated immunity induced by recombinant Mycobacterium bovis Bacille-Calmette-Guerin strains against an intracellular bacterial pathogen: Importance of antigen secretion or membrane-targeted antigen display as lipoprotein for vaccine efficacy. J. Immunol. 168: 1869-1876.
 

Collins, H., U. Schaible, and S.H.E. Kaufmann (1998). Early IL-4 induction in bone marrow lymphoid precursor cells by mycobacterial lipoarabinomannan. J. Immunol. 161: 5546-5554.
 

Züel, U., A.-M. Sponaas, J. Neckermann, B. Schoel, and S.H.E. Kaufmann (2001). Gp96-peptide vaccination of mice against intracellular bacteria. Infect. Immun. 69: 4164-4167.
 

Behr-Perst, S.I., M.E. Munk, T. Schaberg, T. Ulrichs, R.-J. Schulz, and S.H.E. Kaufmann (1999). Phenotypically activated  γδ T lymphocytes in the peripheral blood of patients with tuberculosis. J. Infect. Dis 180:141-149.
 

Seiler, P., P. Aichele, B. Raupach, B. Odermatt, U. Steinhoff, and S.H.E. Kaufmann (2000). Rapid neutrophil response controls fast replicating intracellular bacteria, but not slow replicating Mycobacterium tuberculosis. J. Infect. Dis. 181: 671-688.
 

Schaible, U.E., K. Hagens, K. Fischer, H.L. Collins, and S.H.E. Kaufmann (2001). Intersection of group I CD1 molecules and mycobacteria in different intracellular compartments of dendritic cells. J. Immunol. 164: 4843-4852.
 

Rolph, M., B. Raupach, H. Köbernick, B. Perarnau, F. Lemonnier, and S.H.E. Kaufmann (2001). MHC class Ia-restricted T cells partially account for β2-microglobulin-dependent resistance to Mycobacterium tuberculosis. Eur. J. Immunol. 31: 1944-1949.
 

Fischer, K., D. Chaterjee, J. Torrelles, P.J. Brennan, S.H.E. Kaufmann, and U.E. Schaible (2001). Mycobacterial lysocardiolipin is exported from phagosomes upon cleavage of cardiolipin by a macrophage-derived lysosomal phospholipase A2. J. Immunol. 167: 2187-2192.
 

Fischer, K., H. Collins, M. Taniguchi, S.H.E. Kaufmann and U.E. Schaible (2002). IL4 and T cells are required for the generation of IgG1 isotype antibodies against cardiolipin. J. Immunol. 168:2689-2694.
 

Schaible U.E., H.L. Collins, F. Priem and S.H. E. Kaufmann (2002). Correction of the iron overload defect in beta-2-microglobulin knockout mice: lactoferrin abolishes their increased susceptibility to tuberculosis. J. Exp. Med. 196: 1507-1513.
 

Frishman D., Albermann K., Hani J., Heumann K., Metanomski A., Zollner A., Mewes H.-W. (2001). Functional and structural genomics using PEDANT. Bioinformatics, 17, 44-57.
 

Terwilliger, T.C., Park, M.S., Waldo, G.S., Berendzen, J., Hung, L.W., Kim, C.Y., Smith, C.V., Sacchettini, J.C., Bellinzoni, M., Bossi, R., De Rossi, E., Mattevi, A., Milano, A., Riccardi, G., Rizzi, M., Roberts, M.M., Coker, A.R., Fossati, G., Mascagni, P., Coates, A.R., Wood, S.P., Goulding, C.W., Apostol, M.I., Anderson, D.H., Gill, H.S., Eisenberg, D.S., Taneja, B., Mande, S., Pohl, E., Lamzin, V., Tucker, P., Wilmanns, M., Colovos, C., Meyer-Klaucke, W., Munro, A.W., McLean, K.J., Marshall, K.R., Leys, D., Yang, J.K., Yoon, H.J., Lee, B.I., Lee, M.G., Kwak, J.E., Han, B.W., Lee, J.Y., Baek, S.H., Suh, S.W., Komen, M.M., Arcus, V.L., Baker, E.N., Lott, J.S., Jacobs, W., Alber, T. & Rupp, B. (2003). The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology. Tuberculosis 83, 223-249.
 

Wilmanns, M. (2002). Integrated Structural Genomics in Europe. Gene Funct. Dis. 3, 18-24.